Insulin 100 News

New publications on the Insulin discovery

Good friend of our club, Dr Kenneth McHardy of Aberdeen, has published a wonderful article, “Realigning history: The Toronto Four insulin discovery team,” in the Journal of the Royal College of Physicians of Edinburgh. McHardy describes the decades of effort made to properly recognize the role Professor JJR Macleod played in the insulin discovery of 1921-23 in Toronto. Through the work of John Otto and Kimberlie Hamilton, a striking memorial statue of Macleod was created in Aberdeen’s Duthie Park. Last September 2024, the Toronto Medical Historical Club was proud to participate in a celebration marking the addition of four bronze plaques memorializing the “Toronto Four”–Frederick Banting, Charles Best, JB Collip and JJR Macleod–the collaborators who gave clinically-useful insulin to the world.

This month also marks the publication of a new edition of Michael Bliss’s classic work, The Discovery of Insulin by the University of Chicago Press. This enlarged edition features a new preface written by Bliss shortly before his death in 2017 and a foreword by Alison Li.

Bliss’s riveting work tells the story of one of the most significant breakthroughs in modern medicine, one that has saved the lives of hundreds of millions of people living with diabetes. The collaboration of Frederick Banting, Charles Best, James Bertram Collip and John James Rickard Macleod in Toronto from 1921-23 was at times fractious, but proved key to the ultimate success of their venture. The Discovery of Insulin remains the definitive account of these remarkable events, and with this new edition, it is sure to captivate a new generation of readers. 

Insulin 100 News

Toronto Four Symposium & Celebration in Aberdeen

Toronto Four Celebration Duthie Park, Aberdeen [Photo: Aberdeen Photo]

View the “Toronto Four” Symposium videos, University of Aberdeen, 6 September 2024


Club members John Dirks, Peter Kopplin, Christopher Rutty and Alison Li, along with colleagues Gary Goldberg, Erling Norrby of Stockholm and James Wright of Calgary and partners Christine Kopplin, Andrea Rutty, and Elsebeth Welander-Berggren were warmly welcomed to Aberdeen by John Otto and Kimberlie Hamilton, co-founders of the JJR Macleod Memorial Statue Society, and by our good friend Kenneth McHardy.

Unveiling of Toronto Four plaques
Unveiling of Toronto Four plaques. Gary Goldberg, Erling Norrby, John Otto, John Dirks, Kenneth McHardy, Peter Kopplin [Photo: Aberdeen Photo]
News

Freeze-dried blood serum from the 1940s gives hope to researchers of today

Kanwal Singh from Defence Research and Development Canada helped Dr. Beckett take freeze-dried plasma from 1943, which this empty bottle once contained, and see how well it had held up over time. [Photo: SAMMY KOGAN/THE GLOBE AND MAIL]

Club member Christopher Rutty is featured in this fascinating story that appears in today’s Globe & Mail. Dr Rutty is resident historian and manager of the Sanofi Toronto archives where an 80-year old bottle in a museum display-case provided striking evidence of the value of freeze-dried blood serum.

Events

Celebrating the 100th Anniversary of the Nobel Prize for the Discovery of Insulin to Banting and Macleod: Impact and Legacy

Nobel Laureate Dr Arthur Mcdonald; Professor Erling Norrby of Stockholm; Her Excellency Signe Burgstaller, Ambassador of Sweden to Canada; Nobel Laureate John Polanyi; Dr John Dirks

On November 27, 2023, the Toronto Medical Historical Club hosted a successful symposium celebrating the 100th anniversary of the award of the Nobel Prize in Physiology or Medicine to Frederick Banting and JJR Macleod for the discovery of insulin. The event brought together a distinguished panel of speakers to reflect on the impact and legacy of the insulin discovery and to inspire future research advancement.

Insulin 100 News

“It Works! Now What?” by Christopher Rutty

Photograph of the Connaught Laboratories ca. 1923 [UToronto, Insulin collection]

Congratulations to Christopher Rutty whose new article ““It Works! Now What?” Insulin Development, Production, and Distribution at Connaught Laboratories, University of Toronto, 1922–24″ appears in the Canadian Journal of Health History.

Chris’ article focuses on Connaught’s intimate involvement in the history of insulin from January 1922 through the summer of 1924, tracing the challenges and innovations of developing larger-scale production methods, the establishment and expansion of Canadian insulin production capacity, and the key role the labs played in spearheading the global distribution of insulin.